homeabout kottke.orgarchives + tags

kottke.org posts about science

Should we use CRISPR to engineer mosquitoes incapable of transmitting malaria?

posted by Jason Kottke   Sep 21, 2016

Thousands of people die every day from malaria, a disease that is transmitted to humans solely through mosquitoes. With CRISPR, scientists can easily genetically engineer mosquitoes incapable of transmitting malaria and using a technique called gene drive, they can force that genetic change into the native mosquito population. So, should we do it?

We Work Remotely

A timeline of the Earth’s average temperature

posted by Jason Kottke   Sep 13, 2016

XKCD Climate Change

From XKCD, a typically fine illustration of climate change since the last ice age ~20,000 years ago.

When people say “the climate has changed before”, these are the kinds of changes they’re talking about.

And then in the alt text on the image:

[After setting your car on fire] Listen, your car’s temperature has changed before.

The chart is a perfect use of scale to illustrate a point about what the data actually shows. Tufte would be proud.

Update: Tufte is proud. (via @pixelcult)

Watch time lapse videos of bacteria evolving drug resistance

posted by Jason Kottke   Sep 09, 2016

Researchers at Harvard have come up with a novel way of studying how bacteria evolve to become drug resistant. They set up a large petri dish about the same shape as a football field with no antibiotics in the end zones and increasingly higher doses of antibiotics toward the center. They placed some bacteria in both end zones and filmed the results as the bacteria worked its way toward the center of the field, evolving drug resistance as it went. Ed Yong explains:

What you’re seeing in the movie is a vivid depiction of a very real problem. Disease-causing bacteria and other microbes are increasingly evolving to resist our drugs; by 2050, these impervious infections could potentially kill ten million people a year. The problem of drug-resistant infections is terrifying but also abstract; by their nature, microbes are invisible to the naked eye, and the process by which they defy our drugs is even harder to visualise.

But now you can: just watch that video again. You’re seeing evolution in action. You’re watching living things facing down new challenges, dying, competing, thriving, invading, and adapting — all in a two-minute movie.

Watch the video…it’s wild. What’s most interesting — or scary as hell — is that once the drug resistance gets going, it builds up a pretty good momentum. There’s a pause at the first boundary as the evolutionary process blindly hammers away at the problem, but after the bacteria “learn” drug resistance, the further barriers are breached much more quickly, even before the previous zones are fully populated.

Scientists discover giraffes are actually four separate species

posted by Jason Kottke   Sep 09, 2016

Giraffe Species

Suddenly, there are four species of giraffe now. Previously there was only one. Scientists have analyzed the genetic code of hundreds of giraffes in Africa and found much variation in their DNA, enough to split one species into four.

Some of the differences were as large or larger than the differences between brown bears and polar bears.

Despite their similar appearances, members of the different species don’t appear to mate with each other. It’s amazing that scientists didn’t know this until now.

The Kingdom of Speech

posted by Jason Kottke   Aug 29, 2016

Kingdom Of Speech

In his new book The Kingdom of Speech, Tom Wolfe argues that speech and not evolution is responsible for the many achievements of humans. Wolfe, the author of The Right Stuff and The Electric Kool-Aid Acid Test, went on NPR the other day to talk about the book. This comment about Darwin’s view of speech stuck out (emphasis mine):

He could not figure out what it was. He assumed, because of his theory, that everything evolved from animals. And didn’t even include it in his theory, language, until he decided that it came from our imitation of the cries of birds. And I think it’s misleading to say that human beings evolved from animals — actually, nobody knows whether they did or not. There are very few physical signs, aside from the general resemblance of apes and humans. The big evolution, if you want to call it that, is that this one species, Homo sapiens, came up with this ingenious trick, which is language.

It’s one thing to say that speech did not evolve from the utterances of previous animals and was instead invented by humans, but it’s quite another to assert that humans did not evolve from animals at all.1 Gonna be fun to sit back and watch the controversy roil on this one. (via @JossFong who said “lazy saturday, just listening to @NPR when ….. WHAT”)

  1. Q: Where does Tom Wolfe get his water?

    A: From a “Well, actually…”

Our potential neverending hot American summer

posted by Jason Kottke   Aug 22, 2016

The frying of America

In today’s installment of terrifying graphics about climate change, the NY Times made a series of three maps showing the potential rise of 100 degree temperatures across the United States if current greenhouse gas emission trends continue through the end of this century. Look at the areas in orange and red on the 1991-2010 map: what sort of landscape do you picture? Keeping that landscape picture in your mind, look at the orange and red areas on the 2060 and 2100 maps. Yep! And Phoenix with 163 days above 100 degrees — that’s every day from March 25th to September 4th over 100 degrees.

P.S. A word about climate change and rising temperatures. The temperature that climate scientists typically reference and care about with regard to climate change is “the average global temperature across land and ocean surface areas”. According to the NOAA, the average temperature of the Earth in the 20th century was 13.9°C (57.0°F). In 2015, the average global temperature was 0.90°C (1.62°F) above that.

In order to avoid dangerous effects of climate change, climate scientists advocate keeping the global average temperature increase below 2 degrees (and more recently, below 1.5 degrees). In late 2015, 195 nations came together in Paris and agreed to:

[Hold] the increase in the global average temperature to well below 2°C above pre-industrial levels and to pursue efforts to limit the temperature increase to 1.5°C above pre-industrial levels, recognizing that this would significantly reduce the risks and impacts of climate change

That’s degrees Celsius, not Fahrenheit. I don’t know about you, but as an American, when I hear 2 degrees, I think, oh, that’s not bad. But 2°C is an increase of 3.6°F, which does seem significant.

Note also that it specifies keeping the temperature “below pre-industrial levels” and not below 20th century levels. It is maddeningly difficult to track down an exact figure for the pre-industrial global temperature, partially because of a lack of precise data, partially because of politics, and partially because of the impenetrability of scientific writing. From a piece Eric Holthaus wrote for FiveThirtyEight earlier this year:

It sounds easy enough to measure global warming: see how hot it was, compare it to how hot it used to be. But climate scientists have several ways of measuring how hot it used to be. NASA’s base period, as I mentioned above, is an average of 1951-80 global temperatures, mostly because that was the most recently available 30-year period when the data set was first created. By chance, it’s also pretty representative of the world’s 20th-century climate and can help us understand how much warmer the world has become while many of us have been alive.

Other organizations go further back. The Intergovernmental Panel on Climate Change, the body of climate scientists that was formed to provide assessments to the United Nations, bases its temperature calculations on an 1850-1900 global average. There was about 0.4 degrees of warming between that time period and the NASA base period.

Climate scientists often refer to that 1850-1900 timespan as “pre-industrial” because we don’t have comprehensive temperature data from the 1700s. But meteorologist Michael Mann, director of Penn State University’s Earth System Science Center, has argued that an additional 0.25 degrees of warming occurred between the start of the Industrial Revolution (around 1750) and 1850. Including Mann’s adjustment would bring February 2016 global temperatures at or very near 2 degrees above the “pre-industrial” average.

I now completely understand why some people deny that anthropogenic climate change is happening. Seriously. I looked for more than 30 minutes for a report or scientific paper that stated the average global temperature for 1850-1900 and I couldn’t find one. I looked at UN reports, NASA reports, reports from the UK: nothing. There were tons of references to temperatures relative to the 1850-1900 baseline, but no absolute temperatures were given. Now, I don’t mean to get all Feynman here, but this is bullshit. When the world got together in Paris and talked about a 1.5 degree increase, was everyone even talking about the same thing? You might begin to wonder what the scientists are hiding with their obfuscation.

Anyway, the important point is that according to climate scientists, we are already flirting with 1.5°C of global warming since pre-industrial times. Which means that without action, the spread of those Phoenician temperatures across the circa-2100 United States is a thing that’s going to happen.

Possible Earth-like planet discovered orbiting star nearest Earth

posted by Jason Kottke   Aug 19, 2016

Exoplanet Art

The scientific rumor mill is saying that astronomers in Chile have discovered an Earth-like exoplanet orbiting the star nearest Earth, Alpha Proxima, a mere 4.25 light years away. As they say, “huge if true”.

The hunt for exoplanets has been heating up in recent years. Since it began its mission in 2009, over four thousand exoplanet candidates have been discovered by the Kepler mission, several hundred of which have been confirmed to be “Earth-like” (i.e. terrestrial). And of these, some 216 planets have been shown to be both terrestrial and located within their parent star’s habitable zone (aka. “Goldilocks zone”).

But in what may prove to be the most exciting find to date, the German weekly Der Spiegel announced recently that astronomers have discovered an Earth-like planet orbiting Proxima Centauri, just 4.25 light-years away. Yes, in what is an apparent trifecta, this newly-discovered exoplanet is Earth-like, orbits within its sun’s habitable zone, and is within our reach. But is this too good to be true?

If you read the article, there’s cause for skepticism but an official announcement is coming next week so we’ll know for sure one way or the other.

The other cool thing? If there is a planet there, plans are already underway to build a project to get probes to nearby Alpha Centuri in 20 years, Project Starshot:

In the last decade and a half, rapid technological advances have opened up the possibility of light-powered space travel at a significant fraction of light speed. This involves a ground-based light beamer pushing ultra-light nanocrafts - miniature space probes attached to lightsails - to speeds of up to 100 million miles an hour. Such a system would allow a flyby mission to reach Alpha Centauri in just over 20 years from launch, and beam home images of possible planets, as well as other scientific data such as analysis of magnetic fields.

Perhaps they can redirect their target slightly?

Update: It appears as if the rumors were true. Phil Plait writing at Slate:

The planet, called Proxima Centauri b or just Proxima b (exoplanets are given their star’s name plus a lower case letter in order of discovery, starting with “b”), orbits Proxima every 11.2 days. It has a mass of no less than 1.3 times the Earth’s, so if it’s rock and metal like Earth it’s only a bit bigger. It’s a mere 7.3 million kilometers from the star-a lot closer than Earth’s distance from the Sun of 150 million kilometers!-but Proxima is so faint and cool it receives about two-thirds the amount of light and heat the Earth does. That means that it’s in Proxima’s habitable zone: It’s possible (more or less) that liquid water could exist on its surface.

That’s coooool.

The coming CRISPR revolution

posted by Jason Kottke   Aug 11, 2016

Perfect eyesight. Curing cancer. Designer babies. Super-soldiers. Because of CRISPR, genetic engineering might make tinkering with life as easy as playing with Lego.

Imagine you were alive back in the 1980’s, and were told that computers would soon take over everything — from shopping, to dating, and the stock market, that billions of people would be connected via a kind of web, that you would own a handheld device orders of magnitudes more powerful than supercomputers.

It would seem absurd, but then all of it happened. Science fiction became our reality and we don’t even think about it. We’re at a similar point today with genetic engineering. So let’s talk about it.

Relatedly, I’m finishing up Neal Stephenson’s Seveneves right now and while it starts out as space science fiction, much of the book is concerned with the sort of genetic engineering issues discussed in the video.

The biggest war in animal history

posted by Jason Kottke   Aug 10, 2016

According to theoretical biologist Suzanne Sadedin, the biggest war in animal history (humans included) is happening right now.

Once upon a time there was a tiny brown ant who lived by a swamp at the end of the Paraná River in Argentina. Her name, Linepithema humile, literally means “humble” or “weak”. Some time during the late 1800s, an adventurous L. humile crept away from the swamp where giant river otter played and capybaras cavorted.

She stowed away on a boat that sailed to New Orleans. And she went to war.

Update: And bang, here’s the supporting science in the form of a 2010 study.

Here, we perform inter-continental behavioral analyses among supercolonies in North America, Europe, Asia, Hawaii, New Zealand and Australia and show that these far-flung supercolonies also recognize and accept each other as if members of a single, globally distributed supercolony. Furthermore, populations also possess similar genetic and chemical profiles. However, these ants do show aggression toward ants from South Africa and the smaller secondary colonies that occur in Hawaii and California. Thus, the largest and most dominant introduced populations are likely descended from the same ancestral colony and, despite having been established more than 100 years ago, have diverged very little. This apparent evolutionary stasis is surprising because, in other species, some of the most rapid rates of evolutionary change have occurred in introduced populations. Given the spatial extent of the Argentine ant society we report here, there can be little doubt that this intercontinental supercolony represents the most populous known animal society.

The “25 years and beyond” section of the Facebook product roadmap contains a single word, unlined twice in red ink: ants. Can ants be trained to look at ads though?

Update: Radiolab also did a segment on these ants. (via @minwoolee)

Update: Wow, the Argentine ant is having a bit of a moment…I didn’t expect this to be my most updated post of the week. Annalee Newitz just dropped a long article about their world domination: Meet the worst ants in the world.

UC Berkeley environmental scientist Neil Tsutsui helmed an effort to sequence the genome of L. humile, in part to find out where the invading group had originated. He and an international team of colleagues published the results of their analysis in 2011. They compared the genomes of Argentine ants in California to those of native populations, and Tsutsui told Ars that they were initially surprised by the results. “I was expecting Buenos Aires to be the source, but it was actually a city upstream called Rosario,” he said. “It turns out that in the late 19th century, when the ants were moving around, Rosario was actually a bigger shipping port than Buenos Aires. So it made more sense as a source for introduced populations.”

Genetic evidence supports the idea that the ants made their way from Port Rosario all across the globe. Subsequent sightings of the ants in the United States show that they also hitched rides on trains from New Orleans, ultimately arriving in California in 1904. Trucks probably transported them throughout the state. But how could such fragile creatures survive these journeys in giant machines and go on to found insectile empires? With their countless queens and nomadic lifestyle, they turned out to be the ultimate adapters.

Che Guevara and Lionel Messi are also from Rosario and have taken over the world in their own way. (via @tcarmody)

How it happened: the discovery of bacteria in the 1670s

posted by Jason Kottke   Aug 09, 2016

Antonie van Leeuwenhoek ran a draper’s shop and was a local politician in Delft, Netherlands in the mid-17th century. During this time, he developed an interest in making lenses and hit upon a technique for making lenses with extremely high magnifications for the time, 270x and perhaps even 500x normal magnification. These lenses allowed him to discover that there were tiny organisms living in his mouth.

Ed Yong, Joss Fong, and Julia Belluz discuss van Leeuwenhoek’s achievement and microorganisms in general in the video above and in an interview.

It is undeniable that antibiotics have been a tremendous health good, maybe one of the greatest health goods of all time. They have brought so many infectious diseases to heel and saved so many lives.

But it’s also clear that they have negative effects on our microbiome. So they are indiscriminate weapons. They kill the microbes that we depend upon and that are good for us as well as the ones that are causing disease and causing us harm. They’re like nukes, rather than precision weapons.

So we’re in a difficult situation now, where on the one hand we’re running out of antibiotics, and the rise of antibiotic-resistant bacteria is a huge public health threat. But at the same time we’re aware of the need to preserve the microbiome.

Yong just came out with a book on microbes called I Contain Multitudes. (Perhaps Whitman was speaking literally?)

The Origin of (almost) Everything

posted by Jason Kottke   Aug 09, 2016

Origin Almost Everything

Oh, this new book from Jennifer Daniel and New Scientist looks great: The Origin of (almost) Everything.

Together they take us on a whistle-stop tour from the start of our universe (through the history of stars, galaxies, meteorites, the Moon and dark energy) to our planet (through oceans and weather to oil) and life (through dinosaurs to emotions and sex) to civilization (from cities to alcohol and cooking), knowledge (from alphabets to alchemy) ending up with technology (computers to rocket science). Witty essays explore the concepts alongside enlightening infographics that zoom from how many people have ever lived to showing you how a left-wing brain differs from a right-wing one.

And Stephen Hawking wrote the foreword. You fancy, Jennifer Daniel!

The Perseid meteor shower should be great this year

posted by Jason Kottke   Aug 08, 2016

Perseids

Every year, the Earth moves through the debris from the Swift-Tuttle comet, resulting in the Perseid meteor shower. This year, the Earth is predicted to move through a particularly dense part of the comet’s wake, which may mean twice the number of shooting stars during this year’s shower. Here’s how to watch:

The best way to see the Perseids is to go outside between midnight and dawn on the morning of Aug. 12. Allow about 45 minutes for your eyes to adjust to the dark. Lie on your back and look straight up. Increased activity may also be seen on Aug. 12-13.

I always find these directions confusing, so to be clear: the best viewing for the Perseids is the night of Aug 11 (Thu) into the morning of Aug 12 (Fri). Good luck!

Chemical make-up of movie theater air shifts w/ movie moments

posted by Jason Kottke   Aug 08, 2016

A study undertaken by a group of German scientists suggests that the chemical makeup of the collective breath of movie audiences change in reaction to what’s happening on the screen.

Human beings continuously emit chemicals into the air by breath and through the skin. In order to determine whether these emissions vary predictably in response to audiovisual stimuli, we have continuously monitored carbon dioxide and over one hundred volatile organic compounds in a cinema. It was found that many airborne chemicals in cinema air varied distinctively and reproducibly with time for a particular film, even in different screenings to different audiences. Application of scene labels and advanced data mining methods revealed that specific film events, namely “suspense” or “comedy” caused audiences to change their emission of specific chemicals.

Humpback whales: the Guardian Angels of the sea

posted by Jason Kottke   Aug 03, 2016

There is evidence that humpback whales deliberately disrupt killer whale hunts, saving other animals from being killed by them.

Marine ecologist Robert Pitman observed a particularly dramatic example of this behavior back in 2009, while observing a pod of killer whales hunting a Weddell seal trapped on an ice floe off Antarctica. The orcas were able to successfully knock the seal off the ice, and just as they were closing in for the kill, a magnificent humpback whale suddenly rose up out of the water beneath the seal.

This was no mere accident. In order to better protect the seal, the whale placed it safely on its upturned belly to keep it out of the water. As the seal slipped down the whale’s side, the humpback appeared to use its flippers to carefully help the seal back aboard. Finally, when the coast was clear, the seal was able to safely swim off to another, more secure ice floe.

Pitman has collected 115 incidents of humpbacks messing with orca hunts. (via @unlikelywords)

Permafrost thawing in Russia has led to an anthrax outbreak

posted by Jason Kottke   Aug 01, 2016

A Siberian heatwave has led to permafrost thaws that have released long-dormant anthrax bacteria, resulting in the hospitalization of 13 people and the death of over 1500 reindeer.

Citing earlier work from 2007, they estimated anthrax spores remain viable in the permafrost for 105 years. Buried deeper, the bacteria may be able to hibernate for even longer. At the same time, where meteorological data were available they indicate temperatures in Yakutia are increasing.

“As a consequence of permafrost melting, the vectors of deadly infections of the 18th and 19th centuries may come back,” the scientists warned, “especially near the cemeteries where the victims of these infections were buried.” Cattle grave sites should be monitored, they concluded, and “public health authorities should maintain permanent alertness.”

Another one of those delightful little climate change gotchas, like the near-death of the Great Barrier Reef.

Update: Eric Holthaus talked to some experts and climatologists and yes, pathogens released by warming are something we were warned about and we need to be concerned about it.

Romanovsky says the possibility that additional pathogens may be released from the permafrost, if that is indeed the source, makes it even more important to study this specific outbreak closely. Once in the water supply, in theory, a future pathogen could spread outside the local area, carried by people or by migrating birds or animals.

Though the current outbreak is happening during an unusual period of extreme warmth, Romanovsky says that, “if it gets warmer in the future, and it seems like it will, the thawing permafrost could be massive.” A further degradation of the permafrost would allow more opportunity for the emergence of sequestered microbes.

Israel achieves breakthroughs in freshwater making tech

posted by Jason Kottke   Aug 01, 2016

In the biggest water miracle since Christ walked on the Sea of Galilee,1 Israel has turned certain drought into a surplus of water. Conservation helped — low-flow shower heads, recycling waste water for crop irrigation — but much of the gain came from vastly improved desalinization techniques, which they hope can spread across the region and the world.

We are standing above the new Sorek desalination plant, the largest reverse-osmosis desal facility in the world, and we are staring at Israel’s salvation. Just a few years ago, in the depths of its worst drought in at least 900 years, Israel was running out of water. Now it has a surplus. That remarkable turnaround was accomplished through national campaigns to conserve and reuse Israel’s meager water resources, but the biggest impact came from a new wave of desalination plants.

Perhaps the world won’t end in water wars after all.

Update: Of course, technological advances can affect politics in many ways. Instead of sharing the tech, Israel can use their water advantage to put political pressure on their neighbors, as when Israel cut water supplies to the West Bank earlier this year during Ramadan.

Even without politics, desalinization is problematic…there’s the small matter of where to put all that salt:

Brine disposal is a big problem in much of the Middle East. The gulf, along with the Red and Mediterranean seas, are turning saltier because of desalination by-products — and the region is the epicenter of desalination worldwide, with the United Arab Emirates, Saudi Arabia, Kuwait, Qatar, Bahrain and Oman making up 45 percent of global desalination capacity. This brine is typically twice as salty as seawater, and advanced desalination plants still produce approximately two cubic meters of waste brine for every one cubic meter of clean water.

(thx, jennifer & nathan)

  1. [That’s your lede? Ok, I quit. -ed]

I Contain Multitudes

posted by Jason Kottke   Jul 07, 2016

I Contain Multitudes

Crackerjack science writer Ed Yong is coming out with his very first book in a month’s time. It’s called I Contain Multitudes (good title!) and is about “astonishing partnerships between animals and microbes”.

Every animal, whether human, squid, or wasp, is home to millions of bacteria and other microbes. Ed Yong, whose humor is as evident as his erudition, prompts us to look at ourselves and our animal companions in a new light-less as individuals and more as the interconnected, interdependent multitudes we assuredly are.

The microbes in our bodies are part of our immune systems and protect us from disease. In the deep oceans, mysterious creatures without mouths or guts depend on microbes for all their energy. Bacteria provide squid with invisibility cloaks, help beetles to bring down forests, and allow worms to cause diseases that afflict millions of people.

I will read anything described as “like a David Attenborough series shot through a really good microscope”.

NASA extends the missions of nine spacecraft

posted by Jason Kottke   Jul 05, 2016

While we’re on the subject, NASA announced late last week that they are extending the missions of nine spacecraft sprinkled about the solar system. Included are the New Horizon probe, which will wing off to study an object in the Kuiper Belt after doing so well with Pluto and the rover Opportunity, which was slated for a mission lasting just over 90 days but has now spent more than 12 years exploring the surface of Mars.

The Dawn mission to Ceres is another spacecraft whose duration has been extended, beating long odds. Part of the spacecraft’s functionality had not been working for some time, but was recently repaired.

It was a bit unexpected because Dawn is low on fuel. “Less than a year ago, I would have thought it was ridiculous that the spacecraft would even be operating at this point,” said Marc D. Rayman, the chief engineer for the Dawn mission.

The Dawn spacecraft was designed to use four spinning wheels to pivot in different directions. But at its previous destination, the asteroid Vesta, two of the four wheels overheated and failed. At Ceres, the wheels stayed off, and the spacecraft used its thrusters instead to pivot.

In December, Dawn reached its lowest orbit, just 240 miles above Ceres. Dr. Rayman said he and his team had expected Dawn to exhaust its remaining propellant by March.

But they spun up the wheels again. That succeeded, cutting the use of the thrusters. “It all worked out beautifully,” Dr. Rayman said. That left enough fuel to contemplate doing something more.

Juno successfully enters orbit around Jupiter

posted by Jason Kottke   Jul 05, 2016

After a voyage from Earth lasting almost 5 years, the Juno spacecraft successfully entered Jupiter’s orbit late last night.

The engine burn was tense. 35 minutes is a long time for a spacecraft burn; after 20 minutes it had slowed Juno enough to be in orbit, but not the correct one. It had to continue for another 15 minutes to put the spacecraft on the correct orbit. It worked essentially perfectly. The burn time was off by just one second. That will have no real effect on the orbit.

The 35-minute burn slowed Juno down by more than 1200 mph.

Body of Theseus

posted by Jason Kottke   Jun 29, 2016

How old are different parts of our bodies? Does anything stick around the entire time? The hair on our bodies lasts only a few years. Fingernails are fully replaced every six months. Your skin lasts 2-4 weeks. Even your blood and bones regenerate every so often. There’s at least one part of your body with lasts the whole time you’re alive, which I found somewhat surprising. See the ship of Theseus paradox.

The ship wherein Theseus and the youth of Athens returned from Crete had thirty oars, and was preserved by the Athenians down even to the time of Demetrius Phalereus, for they took away the old planks as they decayed, putting in new and stronger timber in their places, in so much that this ship became a standing example among the philosophers, for the logical question of things that grow; one side holding that the ship remained the same, and the other contending that it was not the same.

How do we know the lifespans of different cells in the body? Carbon-14 levels from nuclear testing done in the 50s and 60s.

Analysis of growth rings from pine trees in Sweden shows that the proliferation of atomic tests in the 1950s and 1960s led to an explosion in levels of atmospheric carbon 14. Now, Jonas Frisen and colleagues at the Karolinska Institute in Stockholm have taken advantage of this spike in C14 to devise a method to date the birth of human cells. Because this test can be used retrospectively, unlike many of the current methods used to detect cell proliferation, and because it does not require the ingestion of a radioactive or chemical tracer, the method can be readily applied to both in vivo and postmortem samples of human tissues.

NASA’s Juno mission to Jupiter

posted by Jason Kottke   Jun 28, 2016

Launched from Earth in August 2011, the Juno probe is due to arrive at Jupiter on July 4, 2016. Once there, it will circle Jupiter 37 times, observing its atmosphere and magnetic fields, before plunging into the giant planet so as not to contaminate Europa with microbes.

Juno’s principal goal is to understand the origin and evolution of Jupiter. Underneath its dense cloud cover, Jupiter safeguards secrets to the fundamental processes and conditions that governed our solar system during its formation. As our primary example of a giant planet, Jupiter can also provide critical knowledge for understanding the planetary systems being discovered around other stars.

With its suite of science instruments, Juno will investigate the existence of a solid planetary core, map Jupiter’s intense magnetic field, measure the amount of water and ammonia in the deep atmosphere, and observe the planet’s auroras.

Juno will let us take a giant step forward in our understanding of how giant planets form and the role these titans played in putting together the rest of the solar system.

Science is great. That video? Maybe not so much.

On the Origins of Life, Meaning, and the Universe Itself

posted by Jason Kottke   Jun 23, 2016

Big Picture Carroll

After an unbelievably stressful and busy winter/spring, I am hoping to find some time to read this summer. One of the books on my short list is Sean Carroll’s The Big Picture, one of those “everything is connected” things I love. From a post by Carroll on what the book’s about:

This book is a culmination of things I’ve been thinking about for a long time. I’ve loved physics from a young age, but I’ve also been interested in all sorts of “big” questions, from philosophy to evolution and neuroscience. And what these separate fields have in common is that they all aim to capture certain aspects of the same underlying universe. Therefore, while they are indisputably separate fields of endeavor — you don’t need to understand particle physics to be a world-class biologist — they must nevertheless be compatible with each other — if your theory of biology relies on forces that are not part of the Standard Model, it’s probably a non-starter. That’s more of a constraint than you might imagine. For example, it implies that there is no such thing as life after death. Your memories and other pieces of mental information are encoded in the arrangement of atoms in your brain, and there’s no way for that information to escape your body when you die.

Yeah, that sounds right up my alley.

How to tell left from right

posted by Tim Carmody   Jun 16, 2016

Not everyone can distinguish between left and right. Besides natural affinity (or lack of it), health, drug use, other chemical changes, and stress can all cause our basic body compass to break down.

Telling left from right necessitates complex brain processes that include spatial perceptions, memory, language, and the integration of sensory information. The task is made increasingly complex when a person must identify laterality on someone else. Yoga teachers and other fitness instructors have it extra rough: While calling out to students to bend their left knee, the instructor has to raise their own right to mirror the class…

However, the field under the most pressure to avoid lateral confusion is medicine. In the dentist’s chair, there’s money wasted when hygienists x-ray the wrong tooth. It’s even worse when a left-right-disoriented dentist pulls one or more teeth from the incorrect side of the mouth. It’s even more serious in general surgery: A 2011 report estimates that there are 40 wrong-site surgeries done weekly in the U.S., and many of those involve mixing up a patient’s left and right. This is a devastating problem: If a doctor removes the healthy kidney and not the cancerous one, the results can be fatal. Wrong eye? Now we have a fully blind patient.

There’s nothing inherent about left, right, up, and down — or what are sometimes called “egocentric coordinates.” Speakers of Guugu Yimithirr in Australia famously use a coordinate system that leans much more heavily on absolute geocentric references at right angles (their equivalent of north, south, east, and west).

This plays a little easier when you’re playing off objects with fixed positions, like landmarks, or especially, the sun, than it does in big twisty-turny cities. But you could imagine in a world with ubiquitous handheld maps and compasses that a north/south/east/west orientation might make more sense.

What’s more, some of the old tech people used to train themselves to distinguish or remember left and right — miming handwriting, or wearing a wristwatch on one arm — aren’t as common or dominant as they once were. See also: distinguishing angular position by analogy with the face of an analog clock.

Either we come up with new tricks and new metaphors, or it’s conceivable that what’s seemed like an intuitive, natural way to think about the relative position of bodies in space could become a whole lot less intuitive for more and more people.

Science and storytelling in Finding Nemo and Finding Dory

posted by Tim Carmody   Jun 16, 2016

Adam Summers is a biomechanist who worked as a consultant on fish behavior and anatomy for Pixar’s Finding Nemo and its sequel, Finding Dory. How do you figure out where and how to stick to the known science (or sneak it in sideways) in a movie about talking fish? It’s not an easy question to answer.

This question is very important for the entertainment industry: does it matter whether you’re right, when you’re telling a story to entertain? Under some circumstances, I don’t think it matters. But with an animated movie about real, living systems, when you use the truth — their complexity and beauty — as a springboard for the story, you add a level of gravitas that is vitally important to creating a broad and deep appeal. A young audience is much more sophisticated than you think, and a story informed by a lot of facts alerts them to the presence of real concepts. I got an e-mail from an eight-year-old about Finding Nemo, explaining that characters could not emerge from a whale’s blowhole if they were in its mouth, because there is no link between the trachea and the oesophagus.

There are over 100 inaccuracies in Finding Nemo, but Summers says only one is a genuine error. (He doesn’t name it, but it might be Mr. Ray, who lists names of classes in his song about aquatic species.) Everything else, from the whale’s blowhole to ignoring clownfish’s ability to switch between male and female (although what if Marlin does become female, but just never spawns again?) is an intentional gloss or omission for storytelling purposes.

Or aesthetic ones. “The claspers — external, stick-like sexual organs on sharks — were cut off Bruce the great white shark,” says Summers, “not because of family values, but because he’s spherical, and when you add a bunch of sticks to spherical sharks, they look really stupid.” Noted.

Summers admits there’s also just a lot about the species in Pixar’s fish movies that nobody really knows.

They did ask me some questions about the biology of whale sharks (Rhincodon typus) that we just don’t know the answers to. It’s the largest fish in the sea, yet I think there’s just one record of a pregnant female, which revealed that they can have more than 300 pups at a time. That’s not much to know about the reproductive biology of such an iconic fish.

The legally blind astronomer

posted by Jason Kottke   Jun 06, 2016

Tim Doucette is a legally blind astronomer. A pair of surgeries when he was younger to help improve his vision left him with a superpower: because his pupils were permanently dilated, he could see in the dark better than other people. He built an observatory and with the aid of his telescope, he can see details of far-off stars and nebula that no one else can, including UV and infrared light.

The Gene: An Intimate History

posted by Jason Kottke   Jun 02, 2016

Siddhartha Mukherjee, who wrote The Emperor of All Maladies, a biography of cancer and one of my favorite recent reads, is out with a new book called The Gene: An Intimate History.

Siddhartha Mukherjee has a written a biography of the gene as deft, brilliant, and illuminating as his extraordinarily successful biography of cancer. Weaving science, social history, and personal narrative to tell us the story of one of the most important conceptual breakthroughs of modern times, Mukherjee animates the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices.

The book comes recommended by Tyler Cowen, who IIRC also recommended Emperor of All Maladies to me.

This book filled in a number of gaps in my knowledge, plus it is engaging to read. Overall it confirmed my impression of major advances in the science, but not matched by many medical products for general use.

This is on the must-read list this summer. Somehow. When I get a second.

Are you your body? And which half of your brain is you?

posted by Jason Kottke   May 31, 2016

Kurzgesagt and CGPGrey collaborated on a pair of videos about the self. The first video considers the human being as a collection of cells. How many of those cells can you take away before you stop being you? And does that question even make sense? The second video notes that if you sever the connection between the two halves of the human brain, they will each seemingly continue to operate as separate entities. But which of those entities is you? Are there two yous?

How do stealth aircraft avoid radar detection?

posted by Jason Kottke   May 31, 2016

The B-2 stealth bomber has a length of 69 feet and a wingspan of 172 feet but possesses the radar profile of a large bird. How does the plane evade radar so effectively?

Neanderthal-built structures found in French cave are astonishingly old

posted by Jason Kottke   May 25, 2016

Bruniquel Cave

In the 90s, Bruniquel Cave was discovered to have a chamber containing an interesting human-built structure made from broken stalagmites. Carbon dating of a burnt bear bone within the chamber put the age of the activity at 47,600 years ago, smack dab in the Neanderthal era in that area. But recently, after a lull in research about these cave structures, analysis of uranium levels in the broken stalagmites resulted in a much older date for the construction: 176,500 years ago.

Nor is it clear how the Neanderthals made the structures. Verheyden says it couldn’t have been one lone artisan, toiling away in the dark. Most likely, there was a team, and a technically skilled one at that. They broke rocks deliberately, and arranged them precisely. They used fire, too. More than 120 fragments have red and black streaks that aren’t found elsewhere in the chamber or the cave beyond. They were the result of deliberately applied heat, at intensities strong enough to occasionally crack the rock. “The Neanderthal group responsible for these constructions had a level of social organization that was more complex than previously thought,” the team writes.

A robotic rocks sorter

posted by Jason Kottke   May 23, 2016

Jller is a machine that sorts stones from a specific river according to their geologic age.

The machine works with a computer vision system that processes the images of the stones and maps each of its location on the platform throughout the ordering process. The information extracted from each stone are dominant color, color composition, and histograms of structural features such as lines, layers, patterns, grain, and surface texture. This data is used to assign the stones into predefined categories.

See also the robotic pancake sorter. (via colossal)