Using a modified iPhone and a fluorescing nanoparticle tattoo, researchers at Northeastern University have found a way to monitor chemicals in the blood without drawing blood.
The team begins by injecting a solution containing carefully chosen nanoparticles into the skin. This leaves no visible mark, but the nanoparticles will fluoresce when exposed to a target molecule, such as sodium or glucose. A modified iPhone then tracks changes in the level of fluorescence, which indicates the amount of sodium or glucose present. Clark presented this work at the BioMethods Boston conference at Harvard Medical School last week.
The tattoos were originally designed as a way around the finger-prick bloodletting that is the standard technique for measuring glucose levels in those with diabetes. But Clark says they could be used to track many things besides glucose and sodium, offering a simpler, less painful, and more accurate way for many people to track many important biomarkers.