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kottke.org posts about Antonie van Leeuwenhoek

A Microscopic Ode to the Tiny Worlds Found in Rainwater Puddles

From the Journey to the Microcosmos YouTube channel, this is an exploration of the tiny worlds contained in rainwater puddles and their connection to the discovery of microbial organisms in the 1670s by Dutch scientist Antonie van Leeuwenhoek. What a trip that must have been, to be the first person to peer microscopically into some water and observe tiny organisms swimming around. (via @JenLucPiquant)


How it happened: the discovery of bacteria in the 1670s

Antonie van Leeuwenhoek ran a draper’s shop and was a local politician in Delft, Netherlands in the mid-17th century. During this time, he developed an interest in making lenses and hit upon a technique for making lenses with extremely high magnifications for the time, 270x and perhaps even 500x normal magnification. These lenses allowed him to discover that there were tiny organisms living in his mouth.

Ed Yong, Joss Fong, and Julia Belluz discuss van Leeuwenhoek’s achievement and microorganisms in general in the video above and in an interview.

It is undeniable that antibiotics have been a tremendous health good, maybe one of the greatest health goods of all time. They have brought so many infectious diseases to heel and saved so many lives.

But it’s also clear that they have negative effects on our microbiome. So they are indiscriminate weapons. They kill the microbes that we depend upon and that are good for us as well as the ones that are causing disease and causing us harm. They’re like nukes, rather than precision weapons.

So we’re in a difficult situation now, where on the one hand we’re running out of antibiotics, and the rise of antibiotic-resistant bacteria is a huge public health threat. But at the same time we’re aware of the need to preserve the microbiome.

Yong just came out with a book on microbes called I Contain Multitudes. (Perhaps Whitman was speaking literally?)