The results of a major new trial, published in the New England Journal of Medicine, indicate that for children who are at risk of developing a peanut allergy, eating peanuts greatly reduces the chance of an allergy. This is pretty huge news.
All the babies were between 4 and 11 months old when they were enrolled, and all had either an egg allergy, severe eczema, or both-putting them at high risk of a peanut allergy down the road. Indeed, 98 of them were already heading in that direction: They tested positive for mild peanut sensitivity in a skin-prick test. This meant that these babies were already churning out antibodies to the peanut protein. Eating peanuts in the future could set off an allergic reaction.
The team divided the babies into two groups. Half were to avoid eating peanut products until they were 5 years old. The other half received at least 6 grams of peanut protein a week, spread across at least three meals, until they were 5 years old. Bamba was the preferred offering, though picky eaters who rejected it got smooth peanut butter.
Around the 5th birthdays of the trial subjects came the big test. The children consumed a larger peanut portion than they were used to in one sitting, and the results were clear-cut. Among 530 children who had had a negative skin-prick test when they were babies, 14% who avoided peanuts were allergic to them, compared with 2% of those who’d been eating them. In the even higher risk group, the children who were sensitized, 35% of the peanut-avoiders were allergic versus just over 10% of the peanut eaters.
Even if further studies confirm these results, will American parents start feeding their infants peanuts? I don’t know…there are lots of similarities to vaccines in play here.
Update: Somewhat related: children in developed countries might be growing up too clean, making them more likely to develop allergies.
The findings are the latest to support the “hygiene hypothesis,” a still-evolving proposition that’s been gaining momentum in recent years. The hypothesis basically suggests that people in developed countries are growing up way too clean because of a variety of trends, including the use of hand sanitizers and detergents, and spending too little time around animals.
As a result, children don’t tend to be exposed to as many bacteria and other microorganisms, and maybe that deprives their immune system of the chance to be trained to recognize microbial friend from foe.
That may make the immune system more likely to misfire and overreact in a way that leads to allergies, eczema and asthma, Hesselmar says.