You can mine Bitcoin by hand with a pencil and paper.

The SHA-256 algorithm is surprisingly simple, easy enough to do by hand. (The elliptic curve algorithm for signing Bitcoin transactions would be very painful to do by hand since it has lots of multiplication of 32-byte integers.) Doing one round of SHA-256 by hand took me 16 minutes, 45 seconds. At this rate, hashing a full Bitcoin block (128 rounds) would take 1.49 days, for a hash rate of 0.67 hashes per day (although I would probably get faster with practice). In comparison, current Bitcoin mining hardware does several terahashes per second, about a quintillion times faster than my manual hashing. Needless to say, manual Bitcoin mining is not at all practical.