King Tut's family tree Aug 25 2010
According to DNA analysis described in the latest issue of National Geographic, Tutankhamun's parents were most likely brother and sister, which may have contributed to his early death.
In my view, however, Tutankhamun's health was compromised from the moment he was conceived. His mother and father were full brother and sister. Pharaonic Egypt was not the only society in history to institutionalize royal incest, which can have political advantages. But there can be a dangerous consequence. Married siblings are more likely to pass on twin copies of harmful genes, leaving their children vulnerable to a variety of genetic defects. Tut ankhamun's malformed foot may have been one such flaw. We suspect he also had a partially cleft palate, another congenital defect. Perhaps he struggled against others until a severe bout of malaria or a leg broken in an accident added one strain too many to a body that could no longer carry the load.
It's likely that Tut's wife was his half-sister as well.